Parkinson's: Genetic and Environmental Factors

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Subject:   Parkinson's: Genetic and Environmental Factors
Date:     Tue, 21 May 2002 08:46:17 -0400
From:      Stephen Tvedten <steve@getipm.com>
Organization:     Get Set Inc. (www.getipm.com)

To:     Paul Helliker <phelliker@cdpr.ca.gov>
          Director, State of California, Department of Pesticide Regulation 

cc:    Christine Whitman whitman.christine@epa.gov

"Parkinson's disease shows similar characteristics. A protein called alpha-synuclein misfolds and aggregates in the brain in plaques called Lewy bodies. Protofibrils of synuclein have been detected in patients' cells and appear to be toxic. Certain genes and environmental factors, like exposure to a pesticide called rotenone, ultimately increase the misfolding process."

http://www.nytimes.com/2002/05/21/health/21PROT.html?pagewanted=print&position=bottom


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