Research on Fenthion and West Nile Virus
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Pesticide Comments
Date:
Tue, 17 Sep 2002 09:38:06 -0400
From:
Stephen Tvedten <steve@getipm.com>
Organization: Get Set Inc. (www.getipm.com)
To: Paul Helliker <phelliker@cdpr.ca.gov>
Director, State of California, Department of Pesticide
Regulation
cc: Christine Whitman whitman.christine@epa.gov
I used HSDB/TOXNET: to help
interpret the pesticides below.
http://toxnet.nlm.nih.gov
--
O,O,S-trimethyl phosphorothioate is
one of the major photodegradation products of SUPRACIDE, a non-systemic
insecticide controlling a wide range of sucking and leaf-eating insects with
a specific use against scale insects. /Methidathion/ is used in the
control of scale insects, leaf eaters, and some mites.
<snip>
Formulations/Preparations:
Methidathion + DDT.
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O,O,S-trimethyl phosphorothioate is
an an impurity in malathion.
--
Photolysis of thin films of fenthion via sunlight yielded O,S,S-trimethyl
phosphorodithioate and O,O,O-trimethyl phosphorothioate as the major
photodegradation products(3).
FENTHION is a contact and stomach insecticide with useful penetrant & persistent action. It is effective, for example, against fruit flies, leaf hoppers & cereal bugs. Fenthion (Tiguvon) is poured along the backline of cattle before migrating larvae of Hypoderma lineatum and H bovis reach this region. The migrating larvae are killed before they inflict damage to the tissue and the hide over the back.
Fenthion is an analogue of parathion.
About 40% applied to aquatic areas in CA [California?] as an insecticide
for control of mosquitoes, most of the balance is believed to have been used
for mosquito control elsewhere in the U.S. (1974).
-----------------------
O,S,S-Trimethyl phosphorodithioate (TMPDT) and O,O,S-trimethyl
phosphorothioate (TMPT), 2 impurities present in technical formulations
of phenthoate, were examined for their inhibiting effects on the esterase
degradation of (phenyl-14)C-phenthoate in vitro.
The active ingredient is no longer contained in any registered pesticide products ... "cancelled." [USEPA/OPP; Status of Pesticides in Registration, Reregistration and Special Review p.198 (Spring, 1998) EPA 738-R-98-002]
Phenthoate was an insecticide; acaricide...useful for protection of rice,
vegetables, fruits, and tea against chewing and sucking insects.
______________________________________________
FURADAN; Furadan G; FURADAN 3G; FURADAN 4F are some of the synonyms and
identifiers for carbofuran, a
chlolinesterase inhibiting organophosphate insecticide.
http://ace.orst.edu/cgi-bin/mfs/01/tibs/cholines.htm
_____________
Possible association found between Chlordane and heptachlor & neuroblastomas,
aplastic anemias, and acute leukemia. [INFANTE PF ET AL; SCAND J WORK ENVIRON
HEALTH 4 (2): 137-50 (1978)]**PEER REVIEWED**
Chlordane is a very dangerous chlorinated hydrocarbon insecticide and
termaticide.
Malathion has been used in some parts of the country for mosquitoes; very
dangerous organophosphate pesticide.
-------------------------------------------------------------------
Biologic Markers in Immunotoxicology (1992) from
the National Academy Press.
MARKERS OF IMMUNOTOXICITY [page 70]
Classes and Chemicals Causing Immunologic Response
Class Polyhalogenated aromatic hydrocarbons
Examples: TCDD (tetrachlorinated dibenzo-p-dioxin), PBBs (Polybrominated
biphenyls), PCBs (polychlorinated biphenyls), hexachlorobenzene
Metals: Lead, calcium [?], arsenic, methyl mercury
Aromatic hydrocarbons (solvents): Examples: Benzene, toluene.
Polycycling aromatic hydrocarbons: DMBA (dimethylbenzanthracene); B[a]P (benzo[a]pyrene); MCA (methylcholanthrene)
Pesticides: Trimethyl phosphorothioate, carbofuran, chlordane, malathion.
Organotins: TBTO bis (tris-n-butylin) oxide
Aromatic amines: Benzidene, acetyl aminofluorene
Oxidant gases: Nitrogen dioxide, ozone, sulfur dioxide
Particles: Silica, asbestos [both human carcinogens]
Natural products: Selected vitamins, antibiotics, vinca alkaloids, estrogen, plant alkaloids, mycotoxins.
Drugs of abuse: Ethanol, cannabinoids, cocaine, opioids
Therapeutic drugs: Diphenylhydantoin, lithium
Others: Nitrosamine, BHA
http://books.nap.edu/books/0309043891/html/70.html
http://books.nap.edu/books/0309043891/html/71.html#pagetop
Excerpts:
Aromatic hydrocarbons are widespread in the environment and are primarily used in commercial production of industrial chemicals, pesticides, flame retardents, and heat conductors. Dioxins and PCBs produce myelosuppression, immunosuppression, thymic atrophy, and inhibition of immune complement system components in almost all species tested, including primates. TCDD, is an extremely potent immunosuppressant in mice. A dose of 1-2 milligrams per killogram of body weight is all that is required to reduce immune function by 50 percent.
I urge you take the time to read this. It may explain why so many people may be dying from the West Nile Virus in Louisiana. These chemicals are here. They do compromise the immune system based on animal studies and leave animals susceptible to infections, bacteria, parasites, viruses, and possibly some cancers, as well as other diseases.
Bunny Snow
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