New Material At OurStolenFuture.org
Subject: New Material At OurStolenFutere.org
Date: Sun, 3 Nov 2002 05:51:52 -0500
From: Stephen Tvedten <steve@getipm.com>
Organization: Get Set Inc. (www.getipm.com)To: Paul Helliker <phelliker@cdpr.ca.gov>
Director, State of California, Department of Pesticide Regulationcc: Christine Whitman whitman.christine@epa.gov
A great deal of new material has been published recently on www.OurStolenFuture.org
A sample below, with links. For a full list in chronological order, visit www.OurStolenFuture/new/newstuff.htm
It turns out we're not winning the war against cancer: A study published in the Journal of the National Cancer Institute reveals that biases built into standard analyses of cancer incidence data were obscuring the fact that rates of breast, prostate and several other cancers continue to increase in the United States. The old methods had falsely indicated that these and other cancer rates were either flat or decreasing.
• http://www.ourstolenfuture.org/NewScience/human/cancer/2002/2002-1016cleggetal.htmDutch scientists report that boys exposed prenatally to higher levels of PCBs and dioxin are more likely to show demasculinized play behaviors. Girls and boys exposed to modestly elevated dioxin levels demonstrate more feminized play behaviors. The scientists suggest that that these alterations in play result from endocrine disruption of the development of sex-specific behaviors.
• http://www.ourstolenfuture.org/NewScience/behavior/2002/2002-09vreugdenhiletal.htmA combined lab and field study of the leopard frog implicates atrazine in widespread feminization of males during tadpole development and metamorphosis. The lab studies confirmed earlier findings from a different amphibian, the African clawed toad, that extremely low levels of atrazine causes significant gonadal abnormalities in male frogs. The field studies demonstrate widespread abnormalities in wild populations of the frog and link them to the geography of atrazine use.
• http://www.ourstolenfuture.org/NewScience/wildlife/frogs/2003/2003-1023hayesetal.htmWriting in the New Scientist, reporter Andy Coghlan describes intriguing new research indicating that sexual differentiation of the brain begins before the activation of a gene that determines whether an individual develops testes or ovaries. "Till now, the orthodoxy among developmental biologists has been that embryos develop ovaries and become female unless a gene called SRY on the Y chromosome is switched on. If this gene is active, it makes testes develop instead." New research by a group of California scientists has revealed sexual differences in gene activation in the brain before the SRY gene activity is initiated. This research may help understand the biological basis of "why some people feel trapped in a body of the wrong sex."
• http://www.ourstolenfuture.org/Commentary/News/2002/2002-1019-NS-brainsex.htmA ten-year study of the brain structure reports that children with attention-deficit/hyperactivity disorder (ADHD) have brains significantly smaller than normal. The size differences are apparent in early childhood, at the earliest ages examined in the study. The authors conclude that ADHD is a biologically-based disorder with clear structural differences, and that the events initiating ADHD are likely to occur in the womb.
• http://www.ourstolenfuture.org/NewScience/behavior/2002/2002-10castellanosetal.htmUsing new analytical methods, a team of German scientists measured bisphenol A in the blood of pregnant women, in umbilical blood at birth and in placental tissue. All samples examined contained BPA, at levels within the range shown to alter development in laboratory experiments with animals. Thus widespread exposure to BPA at levels of concern is no longer a hypothetical issue. It is occurring.
• http://www.ourstolenfuture.org/NewScience/oncompounds/bisphenola/2002/200210schonfelderetal.htmA study by a distinguished group of experts on the effects of diethylstilbestrol, including Arthur Herbst, whose research first revealed DES's human toll, reports that exposure to DES in the womb elevates breast cancer risk beginning in a woman's fifth decade of life. The sample size remains small, because DES use was most prevalent in the '50s and '60s and therefore exposed "DES daughters" are only now reaching the age when breast cancer incidence rises substantially. Nevertheless, this new study clearly indicates that DES daughters over 40-yrs old are at greater risk to breast cancer than unexposed women of comparable age.
• http://www.ourstolenfuture.org/NewScience/human/cancer/2002/2002-10palmeretal.htmNew results from scientific studies of people exposed to dioxin during the 1976 chemical plant explosion in Seveso, Italy, reveal that immune system suppression by dioxin continues on at least 2 decades following initial exposure. Higher levels of dioxin correlate strongly with lower levels of a key immune system defense component, immunoglobulin G.
• http://www.ourstolenfuture.org/NewScience/immune/2002/2002-0930baccarellietal.htmResearch at the University of Wisconsin reveals that very low doses of a commercial mixture of lawn chemical herbicides including 2,4-D causes fetal loss in mice. The scientists who conducted the study obtained the herbicides by simply going to a local hardware store and buying a common brand. Tests are usually conducted on pure components of such brands, instead of the actual mixtures sold. Tests with the pure components had indicated exposure at levels used in these experiments should not have caused effects. In fact, the lowest level used in the experiments, which caused significant fetal loss, was one-seventh the level allowed by EPA in drinking water. These results indicate that mixtures must become a focus of regulatory testing for toxicology, and that current standards are not adequate.
• http://www.ourstolenfuture.org/NewScience/reproduction/2002/2002-0917cavieresetal.htm
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